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The Associated Press

BERLIN—Defending champion Ana Ivanovic overcame a slow start before defeating qualifier Akgul Amanmuradova 7-6 (0), 6-2 Wednesday at the German Open.

Top-ranked Justine Henin cruised past Chan Yung-jan 6-0, 6-2, fourth-seeded Jelena Jankovic defeated Peng Shuai 7-5, 6-0, and Victoria Azarenka upset sixth-seeded Anna Chakvetadze 1-6, 7-6 (1), 6-4.

Ivanovic couldn’t break Amanmuradova’s serve in the first set, but shut her out in the tiebreaker with precise drop shots and forehand winners.

The second-ranked Serb took control in the second set against Amanmuradova, who replaced the injured Amelie Mauresmo on Monday.

“This was the tournament that made me. I found my game here,” the 20-year-old Ivanovic said of last year’s win. “Ever since then, I have the confidence to believe I can be a top player.”

In other matches, Svetlana Kuznetsova defeated Catalina Castano 6-3, 6-2, and Agnieszksa Radwanska rolled past Angelika Bachmann 6-1, 6-1.

Two seeded players were beaten. Victoria Azarenka rallied to upset No. 6 Anna Chakvetadze 1-6, 7-6 (1), 6-4, and Maria Kirilenko beat No. 16 Nadia Petrova, 6-3, 6-3.

Henin returns from a break, looking to regain confidence after a 6-2, 6-0 pounding by Serena Williams in her last match at the Sony Ericsson Open in March. It was the most one-sided loss for a No. 1 player in nine years.

In April, Henin pulled out of the Family Circle Cup because of a right knee injury.

“If I can get my confidence back, then it has to be here,” said Henin, a three-time champion. “The German Open has been very good to me.”

The German Open, with 17 of the top 20 players in the field, is expected to establish a favorite for the upcoming French Open.

Ivanovic believes the favorite is Serena Williams, who is riding a 16-match winning streak.

“Henin has mastered clay, but I think the game is getting more powerful, like Serena is playing,” Ivanovic said.

Another Berlin title would rank Ivanovic, a two-time Grand Slam finalist, among the French Open contenders.

“I definitely think I have the game,” the Serb said. “At the French Open final, I was just too nervous. At the Australian, it was better. It’s a learning experience.”