INDIANS 10, ORIOLES 4
BALTIMORE - Cesar Hernandez and Harold Ramirez homered off Baltimore ace John Means, who exited in the first inning with shoulder fatigue, as Cleveland beat the Orioles.
Cedric Mullins homered twice as part of his second career five-hit outing for Baltimore, which saw its three-game winning streak end. Ryan Mountcastle hit a solo shot in the sixth.
Yu Chang also homered to help Aaron Civale (8-2) tie for the major league lead in victories. Cleveland has won three of its last four.
Means (4-2) surrendered a leadoff homer to Hernandez and a solo drive to Ramirez with two outs. After Eddie Rosario followed with a single, Means exited the game.
Phillies 5, Nationals 2
PHILADELPHIA - Bryce Harper hit a run-scoring single that stopped an 0-for-18 skid in his return from the injured list, Andrew McCutchen hit a three-run homer and Philadelphia defeated Washington.
Washington's Josh Harrison was hit by pitches twice, by starter Spencer Howard and by Ranger Surez (1-0), who won by pitching three hitless innings.
Rhys Hoskins had an RBI for Philadelphia, which won for just the second time in the last six games.
Josh Bell went deep for the Nationals.
Connor Brogdon pitched a 1-2-3 ninth for his first save since 2019 at Double-A.
Joe Ross (2-6) gave up four runs - all unearned - and three hits in six innings.
Pirates 8, Marlins 7, 12 Innings
PITTSBURGH - Jacob Stallings hit a game-ending single in the 12th inning that lifted Pittsburgh over Miami and extended the Marlins' longest losing streak in six years to eight games.
Automatic runner Adam Frazier advanced to third on Ke'Bryan Hayes' flyout leading off the 12th against Adam Cimber (1-2). Bryan Reynolds was intentionally walked, and Stallings lined a single to center.
Clay Holmes (2-0) pitched a perfect 12th.
Miami has lost eight in a row for the first time since May 15-22, 2015, and has lost nine of 10, dropping a season-low nine games under .500 at 24-33.
Jorge Alfaro had four hits, including a two-run homer in the fifth for the Marlins.
Cardinals 5, Reds 2
ST. LOUIS - Yadier Molina left the game in the fourth inning with a bruised knee, and St. Louis lost to Cincinnati, the Cardinals' fourth straight setback.
The 38-year-old Molina took a foul tip off the bat of Kyle Farmer off his left knee in the fourth inning, Andrew Knizner pinch hit in the bottom half for Molina and made a run-scoring throwing error in the seventh.
Jonathan India and Eugenio Surez homered for the Reds to back Tyler Mahle (5-2), who allowed two runs and five hits in seven innings with eight strikeouts.
Cincinnati has won three in a row for the first time since a six-game winning streak that started after the Reds lost their opener against the Cardinals.
Ryan Helsley (3-4) took the loss.
Tigers 4, White Sox 3
CHICAGO - Tarik Skubal struck out a career-high 11 to win consecutive starts for the first time in his major league career, Eric Haase homered twice and Detroit beat Chicago.
Chicago manager Tony La Russa remained tied with John McGraw on the career manager wins list at 2,763, behind only Connie Mack at 3,731.
Miguel Cabrera also homered for the Tigers. José Cisnero pitched a perfect ninth for his first career save.
Nick Madrigal and Yon Moncada had two hits apiece for the White Sox, who struck out a season-high 16 times, their 25th game in double digits.
Skubal (3-7) allowed one run and four hits in five innings. He has struck out at least eight in each of his last four outings.
Lucas Giolito (5-5) gave up four runs and seven hits in seven innings, including all three homers, and struck out nine.
Twins 5, Royals 4
KANSAS CITY, Mo. - Ryan Jeffers, Kyle Garlick and Miguel San homered, and Minnesota turned a game-ending double play with the potential tying run at third base to beat Kansas and stop a four-game losing streak.
José Berros (6-2) gave up four runs and six hits in six innings. Hansel Robles picked up his fifth save in seven chances.
Nelson Cruz had two hits, a walk and his first stolen base since 2018. Minnesota homered for the 16th consecutive game, tying the longest streak in club history.
Mike Minor (4-3) allowed five runs and seven hits in seven innings.
Whit Merrifield hit a two-run single and Andrew Benintendi hit a two-run homer for the Royals.
Brewers 7, Diamondbacks 5
MILWAUKEE - Christian Yelich and Omar Narvez hit back-to-back homers in the eighth inning and Milwaukee dealt Arizona its team-record 16th straight road loss.
Devin Williams (2-0) pitched a scoreless eighth and Josh Hader retired the side in order in the ninth for his 14th save in as many chances.
Josh Rojas hit two home runs for Arizona. Joakim Soria (0-2) took the loss.