BOSTON -- Will Brennan hit a pinch-hit, two-run homer in the seventh inning and the Cleveland Guardians beat the Red Sox 6-0 on Monday in Boston's traditional Patriots' Day game.
José Ramirez and Gabriel Arias each added an RBI double for Cleveland, which has started 8-2 on the road.
Wearing their white jerseys with red letters that read "Boston" across the front, which was inspired by the first game back after the Boston Marathon bombings in 2013, the Red Sox were held to three hits.
Boston left fielder Tyler O'Neill had to leave the game in the eighth after colliding with third baseman Rafael Devers when the two were chasing a shallow pop up.
Making his season debut after starting on the injured list due to a viral illness, Guardians starter Xzavion Curry held the Red Sox to two singles over five innings.
ORIOLES 7, TWINS 4
BALTIMORE -- Cedric Mullins saved a run with an exceptional diving catch in deep left-center, then homered and drove in three runs for Baltimore in a victory over Minnesota.
Jordan Westburg drove in two runs during his third career three-hit day, which came two days after his second. Ryan O'Hearn and Gunnar Henderson also homered for the Orioles, who have won five of their six series openers.
Dillon Tate (2-0) got Byron Buxton to pop out with runners on the corners to end the fifth and worked a clean sixth after Baltimore starter Cole Irvin allowed two runs in 4 2/3 innings.
Yennier Cano worked 1 2/3 scoreless innings and cleaned up Keegan Akin's seventh-inning jam, and Craig Kimbrel worked a perfect ninth for his fourth save.
Ryan Jeffers and Jose Miranda each had three hits and two RBIs for Minnesota. Miranda homered and singled in runs, while Jeffers doubled in both runners Cano inherited from Akin.
GIANTS 4, MARLINS 3
MIAMI -- Jung Hoo Lee had two hits, including a tying single in the seventh inning, and San Francisco overcame an early three-run deficit to beat Miami.
Kyle Harrison (2-1) allowed three runs in six innings. The rookie left-hander gave up eight hits, walked one and struck out two.
Down 3-1, the Giants rallied with a three-run seventh against relievers George Soriano (0-1) and Andrew Nardi. Patrick Bailey's sacrifice fly made it 3-2 before consecutive RBI singles from Lee and pinch-hitter Wilmer Flores.
Tyler Rogers relieved Harrison and threw a scoreless seventh, and Ryan Walker got the first two outs in the eighth. Camilo Doval closed, throwing the final 1 1/3 innings for his second save.
Miami's Edward Cabrera struck out 10 and allowed one run and five hits over six innings in his season debut. The right-hander had been sidelined with a right shoulder impingement.
ANGELS 7, RAYS 3
ST. PETERSBURG, Fla. -- Mike Trout's two-run homer highlighted a five-run outburst in the eighth inning and the Los Angeles Angels beat Tampa Bay.
Trout gave the Angels a 2-1 lead with his seventh homer, a 111.1 mph, 420-foot shot down the left-field line off Pat Maton (0-1). Matt Thaiss extended the Angels' lead to 5-1 with three-run double.
Taylor Ward added a two-run homer in the ninth inning off Kevin Kelly, extending the Los Angeles lead to 7-3. The 30-year-old outfielder has 19 RBIs this season.
Reliever Luis Garcia (1-0) worked an inning and earned the win.
Tampa Bay entered with the highest bullpen ERA in the majors at 6.23.
Harold Ramírez had three RBIs, and pulled the Rays within 5-3 with a two-run homer in the eighth inning off Matt Moore.
BLUE JAYS 3, YANKEES 1
TORONTO -- Chris Bassitt pitched into the seventh inning to win his second straight start, Alejandro Kirk reached base three times and Toronto beat New York.
Bassitt (2-2) allowed one run and four hits in 6 1/3 innings. The right-hander walked two and struck out five, ending his outing by fanning Gleyber Torres.
Tim Mayza got two outs and former Yankees reliever Chad Green worked a 1-2-3 eighth. Yimi Garcia retired Juan Soto, Aaron Judge and Anthony Rizzo on flyballs in the ninth for his second save.
Kirk walked and scored in the second and hit an RBI double in the third. His leadoff single in the sixth extended his streak of reaching base safely to seven consecutive plate appearances. Kirk went 2 for 2 with two walks Sunday against Colorado.
New York's Oswaldo Cabrera opened the scoring with an RBI single in the second, but the Blue Jays used a bases-loaded walk and a wild pitch to reply with two runs in the bottom half against right-hander Luis Gil.
METS 6, PIRATES 3
NEW YORK -- Harrison Bader drove in the go-ahead run in the eighth inning for the second day in a row, hitting a two-run double off an angry Aroldis Chapman that lifted the New York Mets over Pittsburgh.
New York overcame a 3-0, sixth-inning deficit and reached .500 for the first time this season. The Mets have won eight of 11 following an 0-5 start under first-year manager Carlos Mendoza.
Chapman (0-1) was ejected by plate umpire Edwin Moscoso for arguing balls and strikes after Bader's double. The Mets stole three bases in the eighth against the Pirates, who have allowed 13 steals this season without throwing out a runner.
A day after hitting his 300th homer, Andrew McCutchen had a go-ahead RBI single off Adrian Houser in a three-run Pirates sixth that included Connor Joe's run-scoring single off Drew Smith and Triolo's sacrifice fly. Joe's hit made him 9 for 17 this season with runners in scoring position.
PHILLIES 2, ROCKIES 1, 10 INNINGS
PHILADELPHIA -- Cristian Pache hit a walk-off single with one out in the 10th inning after Bryce Harper made a leaping, run-saving catch in the top of the frame to lift Philadelphia to a 2-1 win over Colorado.
Colorado Rockies left-hander Kyle Freeland appeared to injure his right, non-throwing shoulder while being used as a pinch-runner in the ninth inning.
Harper also had an RBI single.
Seranthony Domínguez (1-0) pitched a 1-2-3 10th inning. Harper made a leaping grab of Elehuris Montero's liner that likely would've scored automatic runner Nolan Jones from second base.
With Bryson Stott starting on second base in the bottom of the frame, Whit Merrifield moved him to third with a sacrifice bunt. Jake Bird (0-1) got pinch-hitter Alec Bohm to ground out to the drawn-in shortstop before Pache laced the first pitch he saw to right field to score Stott. Pache was in the game after pinch-running for slugger Kyle Schwarber in the eighth.
ROYALS 2, WHITE SOX 0
CHICAGO -- Seth Lugo pitched seven crisp innings, Vinnie Pasquantino homered and Kansas City beat Chicago.
Lugo (3-0) allowed four hits -- all singles -- in his third straight win. The right-hander struck out four and walked one.
Kansas City improved to 5-0 against Chicago already this season. The surprising Royals have allowed a major league-low 48 runs during their 11-6 start, and the White Sox have scored 34 runs so far -- also the lowest total in the big leagues.
Andrew Benintendi had two of Chicago's four hits in its fifth consecutive loss. The White Sox were shut out for the sixth time during their 2-14 start.