How Alzheimer's evolves; how to protect your cognitive powers

Almost 7 million Americans age 65 and older have Alzheimer's disease (AD) -- and three-quarters of them are 75-plus. But AD doesn't just pop up once you're getting Medicare. It's a slowly developing disease that new studies show produces distinct changes in your brain and body over many years.

In 2020, researchers announced a blood test to spot biomarkers that signal AD and allow for early diagnosis. And recently, a 20-year study found that certain biomarkers in cerebrospinal fluid and seen through brain imaging appear in one time sequence in folks who develop AD and in quite another order in those who don't. They included markers for amyloid beta and tau proteins as early as 18 and 14 years, respectively, before AD diagnosis.

The good news: Taking steps while you're younger will reduce your risk for the development of those earliest markers of AD.

Your goals? To maintain a healthy blood flow, normal blood pressure and a healthy weight, manage stress and prevent inflammation. Start by eating a plant-based diet (may include fish like salmon); getting 150-plus minutes of exercise plus 150 minutes of walking weekly; getting 7-8 hours of sleep nightly; having a posse of supportive friends; finding a passion that gives you a sense of purpose and practicing speed of processing games. There are 40 choices shown in at least two studies in humans to keep your brain functioning better. Options are listed in Dr. Mike's book "The Great Age Reboot" and at LongevityPlaybook.com. You can do them in any order, just do them.

Dr. Mike Roizen is the founder of longevityplaybook.com, and Dr. Mehmet Oz is global advisor to iHerb.com, the world's leading online health store. Roizen and Oz are chief wellness officer emeritus at Cleveland Clinic and professor emeritus at Columbia University, respectively. Together they have written 11 New York Times bestsellers (four No. 1's).

King Features Syndicate

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